Journal article

Rapid detection of carbapenemase-producing Pseudomonas spp. using the NitroSpeed-Carba NP test

  • Sadek, Mustafa Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland
  • Poirel, Laurent Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland - INSERM European Unit (IAME), University of Fribourg, Fribourg - Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Fribourg
  • Nordmann, Patrice Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland - INSERM European Unit (IAME), University of Fribourg, Fribourg - Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Fribourg - Institute for Microbiology, University of Lausanne and University Hospital Centre, Lausanne, Switzerland
    01.03.2021
Published in:
  • Diagnostic Microbiology and Infectious Disease. - 2021, vol. 99, no. 3, p. 115280
English The NitroSpeed-Carba NP test was used to rapidly detect and discriminate between the different types of carbapenemases (classes A, B, and D) within 30 minutes among a collection of 202 Pseudomonas sp. strains (mostly Pseudomonas aeruginosa). A total of 99 carbapenemase–(including enzymes exhibiting weak carbapenemase activity such as several Guyana Extended-Spectrum (GES)-ß-lactamases) and 103 non-carbapenemase producers were tested, and the overall specificity and sensitivity were 100% and 99%, respectively. The NitroSpeed-Carba NP test is a rapid, specific, sensitive, and easy-to-implement technique for identification of carbapenemase- producing Pseudomonas spp.
Faculty
Faculté des sciences et de médecine
Department
Médecine 3ème année
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/309265
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