NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol
- Spoel, Steven H. Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands - Developmental, Cell, and Molecular Biology Group, Department of Biology, Duke University, Durham, North Carolina, USA
- Koornneef, Annemart Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
- Claessens, Susanne M. C. Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
- Korzelius, Jerôme P. Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
- Pelt, Johan A. van Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
- Mueller, Martin J. Pharmaceutical Biology, Julius-von-Sachs Institute of Biological Sciences, University of Wuerzburg, Germany
- Buchala, Antony J. Department of Biology, University of Fribourg, Switzerland
- Métraux, Jean-Pierre Department of Biology, University of Fribourg, Switzerland
- Brown, Rebecca Cooperative Research Centre for Tropical Plant Pathology, University of Queensland, St. Lucia, Australia
- Kazan, Kemal Cooperative Research Centre for Tropical Plant Pathology, University of Queensland, St. Lucia, Australia
- Loon, L. C. van Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
- Dong, Xinnian Developmental, Cell, and Molecular Biology Group, Department of Biology, Duke University, Durham, North Carolina, USA
- Pieterse, Corné M. J. Département de Biologie, Université de Fribourg, Switzerland - Graduate School of Experimental Plant Sciences, Section of Phytopathology, Faculty of Biology, Utrecht University, The Netherlands
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21.02.2003
Published in:
- The Plant Cell. - 2003, vol. 15, p. 760
English
Plant defenses against pathogens and insects are regulated differentially by cross-communicating signal transduction pathways in which salicylic acid (SA) and jasmonic acid (JA) play key roles. In this study, we investigated the molecular mechanism of the antagonistic effect of SA on JA signaling. Arabidopsis plants unable to accumulate SA produced 25-fold higher levels of JA and showed enhanced expression of the JA-responsive genes LOX2, PDF1.2, and VSP in response to infection by Pseudomonas syringae pv tomato DC3000, indicating that in wild-type plants, pathogen-induced SA accumulation is associated with the suppression of JA signaling. Analysis of the Arabidopsis mutant npr1, which is impaired in SA signal transduction, revealed that the antagonistic effect of SA on JA signaling requires the regulatory protein NPR1. Nuclear localization of NPR1, which is essential for SA-mediated defense gene expression, is not required for the suppression of JA signaling, indicating that cross-talk between SA and JA is modulated through a novel function of NPR1 in the cytosol.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Biologie
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 5490
- DOI 10.1105/tpc.009159
- Persistent URL
- https://folia.unifr.ch/unifr/documents/300148
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