Eradication of a multidrug-resistant, carbapenemase-producing Klebsiella pneumoniae isolate following oral and intra-rectal therapy with a custom made, lytic bacteriophage preparation
- Corbellino, Mario III Division of Infectious Diseases, Azienda Socio Sanitaria Territoriale (ASST) Fatebenefratelli Sacco, Milano, Italy
- Kieffer, Nicolas Medical and Molecular Microbiology, Faculty of Science and Medicine, Institut National de la Santé et de la Recherche Médicale (INSERM) European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland
- Kutateladze, Mzia G. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia
- Balarjishvili, Nana G. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia
- Leshkasheli, Lika G. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia
- Askilashvili, Lia G. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia
- Tsertsvadze, George G. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia
- Rimoldi, Sara Giordana Division of Microbiology, ASST Fatebenefratelli–Sacco, Milano, Italy
- Nizharadze, Deia Eliava Phage Therapy Center LLC, Tbilisi, Georgia
- Hoyle, Naomi Eliava Phage Therapy Center LLC, Tbilisi, Georgia
- Nadareishvili, Lia Eliava Phage Therapy Center LLC, Tbilisi, Georgia
- Antinori, Spinello III Division of Infectious Diseases, Azienda Socio Sanitaria Territoriale (ASST) Fatebenefratelli Sacco, Milano, Italy - Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milano, Milano, Italy
- Pagani, Cristina Division of Microbiology, ASST Fatebenefratelli–Sacco, Milano, Italy
- Scorza, Daniele Giuseppe Division of Microbiology, ASST Fatebenefratelli–Sacco, Milano, Italy
- Romanò, Ai Ling Loredana Division of Urology, ASST Fatebenefratelli - Sacco, Milano, Italy
- Ardizzone, Sandro Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milano, Milano, Italy - Division of Gastroenterology, ASST Fatebenefratelli - Sacco, Milano, Italy
- Danelli, Piergiorgio Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milano, Milano, Italy - Division of General Surgery, ASST Fatebenefratelli - Sacco, Milano, Italy
- Gismondo, Maria Rita Division of Microbiology, ASST Fatebenefratelli–Sacco, Milano, Italy - Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milano, Milano, Italy
- Galli, Massimo III Division of Infectious Diseases, Azienda Socio Sanitaria Territoriale (ASST) Fatebenefratelli Sacco, Milano, Italy - Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milano, Milano, Italy
- Nordmann, Patrice Medical and Molecular Microbiology, Faculty of Science and Medicine, Institut National de la Santé et de la Recherche Médicale (INSERM) European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland
- Poirel, Laurent Medical and Molecular Microbiology, Faculty of Science and Medicine, Institut National de la Santé et de la Recherche Médicale (INSERM) European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland
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15.04.2020
Published in:
- Clinical Infectious Diseases. - 2020, vol. 70, no. 9, p. 1998–2001
English
In July 2017, a patient presented colonization with a multidrug-resistant, carbapenemase (KPC-3)-producing Klebsiella pneumoniae isolate. A custom-made, lytic bacteriophage preparation was administered to the patient in December 2017, with subsequent eradication of the microorganism and without adverse effects.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
-
- RERO DOC 328654
- DOI 10.1093/cid/ciz782
- Persistent URL
- https://folia.unifr.ch/unifr/documents/308804
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