Rapid detection of fosfomycin resistance in Escherichia coli
- Nordmann, Patrice Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology Faculty of Science and Medicine, University of Fribourg, Switzerland - Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Switzerland - INSERM European Unit (LEA, IAME), University of Fribourg, Switzerland - University Hospital Center and University of Lausanne, Switzerland
- Poirel, Laurent Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology Faculty of Science and Medicine, University of Fribourg, Switzerland - Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Switzerland - INSERM European Unit (LEA, IAME), University of Fribourg, Switzerland
- Mueller, Linda Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology Faculty of Science and Medicine, University of Fribourg, Switzerland - Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Switzerland
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01.01.2019
Published in:
- Journal of Clinical Microbiology. - 2019, vol. 57, no. 1, p. e01531-18
English
The rapid fosfomycin/Escherichia coli NP test was developed to detect fosfomycin resistance in E. coli isolates. The test is based on glucose metabolization and the detection of bacterial growth in the presence of fosfomycin at 40 µg/ml. Bacterial growth is visually detectable by an orange-to-yellow color change of red phenol, a pH indicator. A total of 100 E. coli isolates, among which 22 were fosfomycin resistant, were used to evaluate the test performance. The sensitivity and specificity of the test were 100% and 98.7%, respectively. This new test is user friendly, sensitive and specific, and its results are obtained in 1 h 30 min.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 324139
- DOI 10.1128/JCM.01531-18
- Persistent URL
- https://folia.unifr.ch/unifr/documents/307623
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