Rapid Detection of ESBL-Producing Enterobacteriaceae in Blood Cultures
Dortet, LaurentINSERM U914 ‘Emerging Resistance to Antibiotics’, K.-Bicêtre, France - LabEx LERMIT, Faculté de Médecine Paris Sud, K.-Bicêtre, France
Poirel, LaurentINSERM U914 ‘Emerging Resistance to Antibiotics’, K.-Bicêtre, France - LabEx LERMIT, Faculté de Médecine Paris Sud, K.-Bicêtre, France - Centre National Associé-Centre de Référence des Résistances aux Antibiotiques, K.-Bicêtre, France - Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
Nordmann, PatriceINSERM U914 ‘Emerging Resistance to Antibiotics’, K.-Bicêtre, France - LabEx LERMIT, Faculté de Médecine Paris Sud, K.-Bicêtre, France - Centre National Associé-Centre de Référence des Résistances aux Antibiotiques, K.-Bicêtre, France - Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland - HFR-Hôpital Cantonal, Fribourg, Switzerland
English
We rapidly identified extended-spectrum β-lactamase (ESBL) producers prospectively among 245 gram-negative bacilli–positive cultured blood specimens using the Rapid ESBL Nordmann/Dortet/Poirel test and direct bacterial identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. This combination identified ESBL-producing Enterobacteriaceae within 30 min and had high predictive values.