Clonal distribution of multidrug-resistant Enterobacter cloacae
- Girlich, Delphine INSERM U914 “Emerging Resistance to Antibiotics”, K.-Bicêtre, France
- Poirel, Laurent INSERM U914 “Emerging Resistance to Antibiotics”, K.-Bicêtre, France - Medical and Molecular Microbiology, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland
- Nordmann, Patrice INSERM U914 “Emerging Resistance to Antibiotics”, K.-Bicêtre, France - Medical and Molecular Microbiology, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - Hôpital Cantonal, Fribourg, Switzerland
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2015
Published in:
- Diagnostic Microbiology and Infectious Disease. - 2015, vol. 81, no. 4, p. 264–268
English
A multilocus sequence typing (MLST) scheme including 7 housekeeping genes was used to evaluate whether the current spread of multidrug-resistant Enterobacter cloacae isolates worldwide might be associated to specific successful clones. Fifty E. cloacae clinical isolates of worldwide origin, with various β-lactamase content, and recovered at different periods of time were studied. Forty-four sequence types were identified, highlighting a high clonal diversity with 3 main lineages. This study revealed that a precise identification of the isolates by sequencing of the chromosomal ampC gene of E. cloacae would provide a significant added value to improve the reliability of the MLST scheme.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 255892
- DOI 10.1016/j.diagmicrobio.2015.01.003
- Persistent URL
- https://folia.unifr.ch/unifr/documents/304136
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