Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit in Istanbul, Turkey

Poirel, Laurent; Yilmaz, Mesut; Istanbullu, Ayse; Arslan, Ferhat; Mert, Ali; Bernabeu, Sandrine; Nordmann, Patrice

doi:10.1128/AAC.02047-13

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Journal article

Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit in Istanbul, Turkey

Poirel, Laurent Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, Le Kremlin-Bicêtre, France
Yilmaz, Mesut Infectious Diseases and Clinical Microbiology Department, School of Medicine, Istanbul Medipol University, Turkey
Istanbullu, Ayse Medical Microbiology Department, School of Medicine, Istanbul Medipol University, Turkey
Arslan, Ferhat Infectious Diseases and Clinical Microbiology Department, School of Medicine, Istanbul Medipol University, Turkey
Mert, Ali Infectious Diseases and Clinical Microbiology Department, School of Medicine, Istanbul Medipol University, Turkey
Bernabeu, Sandrine INSERM U914, South-Paris Medical School, Le Kremlin-Bicêtre, France
Nordmann, Patrice Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, Le Kremlin-Bicêtre, France

05.01.2014

Published in:

Antimicrobial Agents and Chemotherapy. - 2014, vol. 58, no. 5, p. 2929–2933

English Twenty-two consecutive carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between January and April 2013 in different units at a university hospital in Istanbul, Turkey. These were Klebsiella pneumoniae isolates producing the carbapenemases OXA-48, NDM-1, and KPC-2, Enterobacter cloacae isolates producing NDM-1, and Escherichia coli isolates producing OXA-48. Most of the OXA-48-producing K. pneumoniae and all the NDM-1-producing E. cloacae were clonally related. The NDM-1-producing E. cloacae isolates recovered from a single neonatal intensive care unit corresponded to a single cluster, highlighting the spread of that clone in that setting.

Faculty

Faculté des sciences et de médecine

Department

Médecine 3ème année

Language