Strategy for a rapid detection of carbapenemase-producing Enterobacteriaceae
- Dortet, Laurent INSERM U914, South-Paris Medical School, K.-Bicêtre, France
- Bréchard, Ludivine INSERM U914, South-Paris Medical School, K.-Bicêtre, France
- Cuzon, Gaëlle INSERM U914, South-Paris Medical School, K.-Bicêtre, France
- Poirel, Laurent INSERM U914, South-Paris Medical School, K.-Bicêtre, France - Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Switzerland
- Nordmann, Patrice INSERM U914, South-Paris Medical School, K.-Bicêtre, France - Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Switzerland
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27.01.2014
Published in:
- Antimicrobial Agents and Chemotherapy. - 2014, vol. 58, no. 4, p. 2441-2445
English
A prospective survey was conducted on 862 Enterobacteriaceae with reduced susceptibility to carbapenems. The Carba NP test, UV spectrophotometry and DNA microarray were used for detecting carbapenemase producers, and results compared to PCR and sequencing. The 172 carbapenemase producers were detected using the Carba NP test and UV spectrophotometry whereas DNA microarray failed to detect IMI producers. Use of the Carba NP test as first screening, followed by the use of molecular techniques has been defined as an efficient strategy for identification of carbapenemase-producing Enterobacteriaceae.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Medicine
- License
- License undefined
- Identifiers
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- RERO DOC 209495
- DOI 10.1128/AAC.01239-13
- Persistent URL
- https://folia.unifr.ch/unifr/documents/303358
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