Rapid detection of carbapenemase-producing Enterobacteriaceae from blood cultures
- Dortet, Laurent Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, France
- Bréchard, Ludivine Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, France
- Poirel, Laurent Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, France - Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
- Nordmann, Patrice Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, France - Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
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2013
Published in:
- Clinical Microbiology and Infection. - 2014, vol. 20, no. 4, p. 340-344
English
The biochemical-based Carba NP test has been evaluated to detect carbapenemase- producing Enterobacteriaceae (n = 193) directly from spiked blood cultures. It was able to rapidly detect KPC (n = 50), IMP (n = 27), VIM (n = 37), NDM (n = 33) and OXA-48-like producers (n = 46) with sensitivity and specificity of 97.9% and 100%, respectively. This cost-effective technique may be implemented in any microbiology laboratory and offers a reliable test for an early identification of carbapenemase- producing Enterobacteriaceae directly from blood culture that could be useful for the management of infected patients.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Pathology, clinical medicine
- License
- License undefined
- Identifiers
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- RERO DOC 118087
- DOI 10.1111/1469-0691.12318
- Persistent URL
- https://folia.unifr.ch/unifr/documents/303124
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