Journal article
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Transfer hydrogenation of ketones and activated olefins using chelating NHC ruthenium complexes
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Horn, Sabine
School of Chemistry & Chemical Biology, University College Dublin,Ireland
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Gandolfi, Claudio
Department of Chemistry, University of Fribourg, Switzerland
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Albrecht, Martin
School of Chemistry & Chemical Biology, University College Dublin,Ireland - Department of Chemistry, University of Fribourg, Switzerland
Published in:
- European Journal of Inorganic Chemistry. - 2011, vol. 2011, no. 18, p. 2863–2868
English
N-Heterocyclic carbene (NHC) ruthenium complexes consisting of different donor substituents attached to the NHC ligand efficiently catalyse the transfer hydrogenation of ketones and of activated olefins in α,β-unsaturated ketones to give saturated alcohols. The most active catalyst precursor contains a tethered olefin as a hemilabile donor site. This complex also converts nitriles and, depending on the reaction conditions, either benzylamines are produced by means of transfer hydrogenation, or amides from formal addition of H₂O. Kinetic analysis of the double hydrogenation of α,β-unsaturated ketones indicates fast isomerisation of the enol intermediate to its saturated ketone tautomer prior to the second hydrogenation.
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Faculty
- Faculté des sciences et de médecine
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Department
- Département de Chimie
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Language
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Classification
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Chemistry
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/302041
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