Journal article

+ 1 other files

Transfer hydrogenation of ketones and activated olefins using chelating NHC ruthenium complexes

  • Horn, Sabine School of Chemistry & Chemical Biology, University College Dublin,Ireland
  • Gandolfi, Claudio Department of Chemistry, University of Fribourg, Switzerland
  • Albrecht, Martin School of Chemistry & Chemical Biology, University College Dublin,Ireland - Department of Chemistry, University of Fribourg, Switzerland
    04.05.2011
Published in:
  • European Journal of Inorganic Chemistry. - 2011, vol. 2011, no. 18, p. 2863–2868
English N-Heterocyclic carbene (NHC) ruthenium complexes consisting of different donor substituents attached to the NHC ligand efficiently catalyse the transfer hydrogenation of ketones and of activated olefins in α,β-unsaturated ketones to give saturated alcohols. The most active catalyst precursor contains a tethered olefin as a hemilabile donor site. This complex also converts nitriles and, depending on the reaction conditions, either benzylamines are produced by means of transfer hydrogenation, or amides from formal addition of H₂O. Kinetic analysis of the double hydrogenation of α,β-unsaturated ketones indicates fast isomerisation of the enol intermediate to its saturated ketone tautomer prior to the second hydrogenation.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/302041
Other files

Statistics

Document views: 17 File downloads:
  • gan_thk.pdf: 15
  • gan_thk_sm.pdf: 2