Horn, Sabine Gandolfi, Claudio Albrecht, Martin 2011-05-04 <em>N</em>-Heterocyclic carbene (NHC) ruthenium complexes consisting of different donor substituents attached to the NHC ligand efficiently catalyse the transfer hydrogenation of ketones and of activated olefins in α,β-unsaturated ketones to give saturated alcohols. The most active catalyst precursor contains a tethered olefin as a hemilabile donor site. This complex also converts nitriles and, depending on the reaction conditions, either benzylamines are produced by means of transfer hydrogenation, or amides from formal addition of H₂O. Kinetic analysis of the double hydrogenation of α,β-unsaturated ketones indicates fast isomerisation of the enol intermediate to its saturated ketone tautomer prior to the second hydrogenation. application/pdf https://folia.unifr.ch/global/documents/302041 https://folia.unifr.ch/documents/302041/files/gan_thk.pdf https://folia.unifr.ch/documents/302041/files/gan_thk_sm.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.1002/ejic.201100143 info:eu-repo/semantics/openAccess License undefined European Journal of Inorganic Chemistry. - 2011, vol. 2011, no. 18, p. 2863–2868 Ruthenium N-Heterocyclic ­carbene Hydrogenation Transfer hydrogenation Ketones Chemoselectivity info:eu-repo/classification/udc/54 Transfer hydrogenation of ketones and activated olefins using chelating NHC ruthenium complexes http://purl.org/coar/resource_type/c_6501