Journal article

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Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation

  • Foukas, Lazaros C. Ludwig Institute for Cancer Research, London, UK
  • Claret, Marc Centre for Diabetes and Endocrinology, University College London, UK
  • Pearce, Wayne Ludwig Institute for Cancer Research, London, UK
  • Okkenhaug, Klaus Ludwig Institute for Cancer Research, London, UK - Babraham Institute, Cambridge, UK
  • Meek, Stephen Gene Targeting Laboratory, The Institute for Stem Cell Research, University of Edinburgh, UK
  • Peskett, Emma Ludwig Institute for Cancer Research, London, UK
  • Sancho, Sara Department of Medicine, University of Fribourg, Switzerland
  • Smith, Andrew J. H. Gene Targeting Laboratory, The Institute for Stem Cell Research, University of Edinburgh, UK
  • Withers, Dominic J. Centre for Diabetes and Endocrinology, University College London, UK
  • Vanhaesebroeck, Bart Ludwig Institute for Cancer Research, London, UK - Department of Biochemistry and Molecular Biology, University College London, UK
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    12.04.2006
Published in:
  • Nature. - 2006, vol. 441, p. 366-370
English The eight catalytic subunits of the mammalian phosphoinositide-3-OH kinase (PI(3)K) family form the backbone of an evolutionarily conserved signalling pathway; however, the roles of most PI(3)K isoforms in organismal physiology and disease are unknown. To delineate the role of p110<img src="/__chars/alpha/black/med/base/glyph.gif" alt="alpha" align="bottom" border="0">, a ubiquitously... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300126
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