Journal article

Influence of TOR kinase on lifespan in C. elegans

  • Vellai, Tibor Department of Biology, University of Fribourg, Switzerland
  • Takacs-Vellai, Krisztina Department of Biology, University of Fribourg, Switzerland
  • Zhang, Yue Department of Biology, University of Fribourg, Switzerland
  • Kovacs, Attila L. Department of General Zoology, Eötvös Loránd University, Budapest, Hungary
  • Orosz, László Department of Genetics, Eötvös Loránd University, Budapest, Hungary - Agricultural Biotechnology Centre, Gödöllö, Hungary
  • Müller, Fritz Department of Biology, University of Fribourg, Switzerland
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    11.12.2003
Published in:
  • Nature. - 2003, vol. 426, p. 620
English The group of enzymes known as TOR (for 'target of rapamycin') kinases regulates cell growth and proliferation in response to nutrients and hormone-dependent mitogenic signals<sup>1, 2</sup>. Here we show that TOR deficiency in the nematode <i>Caenorhabditis elegans</i> more than doubles its natural lifespan. This new function for TOR signalling in ageing control may represent a link between... Show more…
Faculty
Faculté des sciences
Department
Biologie
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300051