Journal article

Over-expression of parvalbumin in transgenic mice rescues motoneurons from injury-induced cell death

  • Dekkers, J. Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London UK
  • Bayley, P. Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London UK
  • Dick, J. R. T. Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London UK
  • Schwaller, Beat Institute of Histology, Department of Medicine, University of Fribourg, Switzerland
  • Berchtold, M. W. Department of Molecular Cell Biology, Institute of Molecular Biology, University of Copenhagen, Denmark
  • Greensmith, L. Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London UK
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    23.12.2004
Published in:
  • Neuroscience. - 2004, vol. 123(2), no. 459-466
English Following nerve injury in neonatal rats, a large proportion of motoneurons die, possibly as a consequence of an increase in vulnerability to the excitotoxic effects of glutamate. Calcium-dependent glutamate excitotoxicity is thought to play a significant role not only in injury-induced motoneuron death, but also in motoneuron degeneration in diseases such as amyotrophic lateral sclerosis... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/299544