Exploring the Potential Role of Manganese-Based Zeolitic Imidazolate Framework Nanoparticles in Cancer Therapy: In vitro Studies Using Lung Cancer Cells

Ivasiv, Viktoriya

doi:10.2147/IJN.S578869

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Journal article

Exploring the Potential Role of Manganese-Based Zeolitic Imidazolate Framework Nanoparticles in Cancer Therapy: In vitro Studies Using Lung Cancer Cells

Ivasiv, Viktoriya ORCID University of Fribourg
Rothen-Rutishauser, Barbara (Contributor) ORCID University of Fribourg, Adolphe Merkle Institute

2026

Published in:

International Journal of Nanomedicine. - 2026, vol. 21, p. 1-21

English Chemodynamic therapy (CDT) has emerged as a promising cancer treatment strategy leveraging tumor microenvironmentconditions to generate reactive oxygen species (ROS) through Fenton-type reactions. This study reports the synthesis, in-depthcharacterization, and biological evaluation of novel manganese-based zeolitic imidazolate framework (ZIF) nanoparticles, ie, Mn-rods, as a carrier-free potential CDT platform with exceptionally high manganese loading.

Faculty

Faculté des sciences et de médecine

Department

Département de Chimie

Language