Exploring the Potential Role of Manganese-Based Zeolitic Imidazolate Framework Nanoparticles in Cancer Therapy: In vitro Studies Using Lung Cancer Cells
- Ivasiv, Viktoriya ORCID University of Fribourg
- Rothen-Rutishauser, Barbara (Contributor) ORCID University of Fribourg, Adolphe Merkle Institute
- 2026
Published in:
- International Journal of Nanomedicine. - 2026, vol. 21, p. 1-21
Chemodynamic therapy
Reactive oxygen species
Tumor microenvironment
Lipid peroxidation
Ferroptosis
Nanomedicine
English
Chemodynamic therapy (CDT) has emerged as a promising cancer treatment strategy leveraging tumor microenvironmentconditions to generate reactive oxygen species (ROS) through Fenton-type reactions. This study reports the synthesis, in-depthcharacterization, and biological evaluation of novel manganese-based zeolitic imidazolate framework (ZIF) nanoparticles, ie, Mn-rods, as a carrier-free potential CDT platform with exceptionally high manganese loading.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Chimie
- Language
-
- English
- Classification
- Biological sciences
- Other electronic version
- License
-
CC BY
- Open access status
- gold
- Identifiers
-
- DOI 10.2147/IJN.S578869
- ISSN 1178-2013
- Persistent URL
- https://folia.unifr.ch/unifr/documents/335025
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