Making genome editing a success story in Africa

Abkallo, Hussein; Arbuthnot, Patrick; Auer, Thomas; Berger, Dave; Burger, Johan; Chakauya, Ereck; Concordet, Jean-Paul; Diabate, Abdoulaye; Di Donato, Vincenzo; Groenewald, Jan-Hendrik; Guindo, Amadou; Koekemoer, Lizette; Nazare, Florence; Nolan, Tony; Okumu, Fredros; Orefuwa, Emma; Paemka, Lily; Prieto-Godino, Lucia; Runo, Steven; Sadler, Marie; Tesfaye, Kassahun; Tripathi, Leena; Wondji, Charles

doi:10.1038/s41587-024-02187-2

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Journal article

Making genome editing a success story in Africa

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Abkallo, Hussein International Livestock Research Institute (ILRI), Nairobi, Kenya
Arbuthnot, Patrick University of the Witwatersrand, Johannesburg, South Africa
Auer, Thomas ORCID University of Fribourg
Berger, Dave University of Pretoria, South Africa
Burger, Johan Stellenbosch University, South Africa
Chakauya, Ereck North-West University, Mmabatho, South Africa
Concordet, Jean-Paul U1154 INSERM, Muséum National d'Histoire Naturelle, Paris
Diabate, Abdoulaye Institut de recherche en sciences de la santé (IRSS), Bobo Dioulasso, Burkina Faso
Di Donato, Vincenzo ZeClinics SL. Sant Feliu de Llobregat, Barcelona
Groenewald, Jan-Hendrik Biosafety South Africa
Guindo, Amadou African Center for Excellence in Molecular Engineering, Mali
Koekemoer, Lizette University of the Witwatersrand, Johannesburg, South Africa
Nazare, Florence African Union Development Agency - NEPAD, Midrand, South Africa
Nolan, Tony Liverpool School of Tropical Medicine, Liverpool, UK
Okumu, Fredros Ifakara Health Institute, Ifakara, Tanzania
Orefuwa, Emma Pan-African Mosquito Association, (PAMCA), KEMRI Headquarters, Nairobi, Kenya
Paemka, Lily University of Ghana
Prieto-Godino, Lucia The Francis Crick Institute, London, UK
Runo, Steven Kenyatta University, Nairobi, Kenya
Sadler, Marie Swiss Institute of Bioinformatics, Switzerland
Tesfaye, Kassahun Addis Ababa University, Ethiopia
Tripathi, Leena International Institute of Tropical Agriculture (IITA), Nairobi, Kenya
Wondji, Charles Liverpool School of Tropical Medicine, Liverpool, UK

2024

Published in:

Nature Biotechnology. - Springer Science and Business Media LLC. - 2024, vol. 42, no. 4, p. 551-554

English Since the development of CRISPR–Cas as a tool for targeted genome manipulation in 2012, genome editing has revolutionized basic and translational research around the globe1. The technology and its potential in bio-innovation were recently highlighted with the approval of the first CRISPR–Cas-based gene therapies for sickle cell anemia and β-thalassemia in humans. However, genome editing is currently underexplored in Africa, where it could be transformative in addressing key challenges in major sectors (including agriculture, public health and medicine).

Faculty

Faculté des sciences et de médecine

Department

Département de Biologie

Language