Mechanically triggered on-demand degradation of polymers synthesized by radical polymerizations
DOKPE
- Liu, Peng ORCID University of Fribourg
- Jimaja, Sètuhn University of Fribourg
- Immel, Stefan ORCID University of Darmstadt, Germany
- Thomas, Christoph ORCID Waters GmbH, Eschborn, Germany
- Mayer, Michael ORCID University of Fribourg
- Weder, Christoph ORCID University of Fribourg
- Bruns , Nico ORCID Swiss National Center of Competence in Research Bio-Inspired Materials, Fribourg, Switzerland
- 2024
Published in:
- Nature Chemistry. - UK : Nature Research. - 2024
English
Polymers that degrade on demand have the potential to facilitate chemical recycling, reduce environmental pollution and are useful in implant immolation, drug delivery or as adhesives that debond on demand. However, polymers made by radical polymerization, which feature all carbon-bond backbones and constitute the most important class of polymers, have proven difficult to render degradable. Here we report cyclobutene-based monomers that can be co-polymerized with conventional monomers and impart the resulting polymers with mechanically triggered degradability. The cyclobutene residues act as mechanophores and can undergo a mechanically triggered ring-opening reaction, which causes a rearrangement that renders the polymer chains cleavable by hydrolysis under basic conditions. These cyclobutene-based monomers are broadly applicable in free radical and controlled radical polymerizations, introduce functional groups into the backbone of polymers and allow the mechanically gated degradation of high-molecular-weight materials or cross-linked polymer networks into low-molecular-weight species.
- Faculty
- Faculté des sciences et de médecine
- Department
- NCCR - Bio-Inspired Materials, Département de Chimie
- Language
-
- English
- Classification
- Chemistry
- Other electronic version
- License
- CC BY
- Open access status
- hybrid
- Identifiers
-
- ISSN 1755-4330
- ISSN 1755-4349
- DOI 10.1038/s41557-024-01508-x
- Persistent URL
- https://folia.unifr.ch/unifr/documents/328252
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