Journal article

Change in Emotional and Theory of Mind Processing in Borderline Personality Disorder : A Pilot Study

IPC

  • Kramer, Ueli Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland. Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland. Department of Psychology, University of Windsor, Canada
  • Kolly, Stéphane Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
  • Maillard, Pauline Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
  • Pascual-Leone, Antonio Department of Psychology, University of Windsor, Canada
  • Samson, Andrea C. ORCID Faculty of Psychology, Swiss Distance Learning University and Swiss Center for Affective Sciences, University of Geneva, Switzerland. Institute of Special Education, University of Fribourg, Switzerland
  • Schmitt, Ruth Department of Psychiatry, University of Heidelberg, Germany
  • Bernini, Adriano LREN – Department of Clinical Neurosciences - CHUV, University of Lausanne, Switzerland
  • Allenbach, Gilles Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
  • Charbon, Patrick Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
  • de Roten, Yves Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
  • Conus, Philippe Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
  • Despland, Jean-Nicolas Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
  • Draganski, Bogdan LREN – Department of Clinical Neurosciences - CHUV, University of Lausanne, Switzerland. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
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  • 2018
Published in:
  • Journal of Nervous & Mental Disease. - Ovid Technologies (Wolters Kluwer Health). - 2018, vol. 206, no. 12, p. 935-943
English Changes in emotion processing (EP) and in theory of mind (TOM) are central across treatment approaches for patients with borderline personality disorder (BPD). Whilst the assessment of EP relies on the observation patient’s self-criticism in a two-chair dialogue, individual’s TOM assessments is made based on responses to humorous stimuli based on false beliefs. For this pilot study, we assessed eight patients with BPD before and after a three-month long psychiatric treatment, using functional magnetic resonance imaging (fMRI) and behavioral tasks. We observed arousal increase within session of the two-chair dialogue (d = 0.36), paralleled by arousal decrease between sessions (d = 0.80). We found treatment associated trends for neural activity reduction in brain areas central for EP and TOM. Our exploratory findings using an integrative assessment procedure of changes in EP and TOM point towards evidence for treatment effects at the brain systems level related to behavioral modulation.
Faculty
Faculté des lettres et des sciences humaines
Department
Département de Pédagogie spécialisée
Language
  • English
License
License undefined
Open access status
green
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/324878
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