Change in Emotional and Theory of Mind Processing in Borderline Personality Disorder : A Pilot Study
IPC
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Kramer, Ueli
Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland. Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland. Department of Psychology, University of Windsor, Canada
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Kolly, Stéphane
Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
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Maillard, Pauline
Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
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Pascual-Leone, Antonio
Department of Psychology, University of Windsor, Canada
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Samson, Andrea C.
ORCID
Faculty of Psychology, Swiss Distance Learning University and Swiss Center for Affective Sciences, University of Geneva, Switzerland. Institute of Special Education, University of Fribourg, Switzerland
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Schmitt, Ruth
Department of Psychiatry, University of Heidelberg, Germany
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Bernini, Adriano
LREN – Department of Clinical Neurosciences - CHUV, University of Lausanne, Switzerland
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Allenbach, Gilles
Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
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Charbon, Patrick
Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
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de Roten, Yves
Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
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Conus, Philippe
Service of General Psychiatry, Department of Psychiatry-CHUV, University of Lausanne, Switzerland
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Despland, Jean-Nicolas
Institute of Psychotherapy, Department of Psychiatry - CHUV, University of Lausanne, Switzerland
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Draganski, Bogdan
LREN – Department of Clinical Neurosciences - CHUV, University of Lausanne, Switzerland. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
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Published in:
- Journal of Nervous & Mental Disease. - Ovid Technologies (Wolters Kluwer Health). - 2018, vol. 206, no. 12, p. 935-943
English
Changes in emotion processing (EP) and in theory of mind (TOM) are central across treatment approaches for patients with borderline personality disorder (BPD). Whilst the assessment of EP relies on the observation patient’s self-criticism in a two-chair dialogue, individual’s TOM assessments is made based on responses to humorous stimuli based on false beliefs. For this pilot study, we assessed eight patients with BPD before and after a three-month long psychiatric treatment, using functional magnetic resonance imaging (fMRI) and behavioral tasks. We observed arousal increase within session of the two-chair dialogue (d = 0.36), paralleled by arousal decrease between sessions (d = 0.80). We found treatment associated trends for neural activity reduction in brain areas central for EP and TOM. Our exploratory findings using an integrative assessment procedure of changes in EP and TOM point towards evidence for treatment effects at the brain systems level related to behavioral modulation.
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Faculty
- Faculté des lettres et des sciences humaines
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Department
- Département de Pédagogie spécialisée
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Language
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License
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License undefined
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Open access status
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green
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/324878
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