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Corona Immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland

  • West, Erin A. Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland
  • Anker, Daniela Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland
  • Amati, Rebecca Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland
  • Richard, Aude Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland - Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland
  • Wisniak, Ania Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland - Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland
  • Butty, Audrey Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Albanese, Emiliano Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland
  • Bochud, Murielle Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Chiolero, Arnaud Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland - Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland
  • Crivelli, Luca Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland
  • Cullati, Stéphane Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland
  • d'Acremont, Valérie Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Epure, Adina Mihaela Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland - Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Fehr, Jan Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland
  • Flahault, Antoine Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland
  • Fornerod, Luc Health Observatory of Valais, Sion, Switzerland
  • Frank, Irène Clinical Trial Unit, Cantonal Hospital Luzern, Luzern, Switzerland
  • Frei, Anja Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland
  • Michel, Gisela Department of Health Sciences and Medicine, University of Luzern, Luzern, Switzerland
  • Gonseth, Semira Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Guessous, Idris Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland
  • Imboden, Medea Swiss Tropical and Public Health Institute, Basel, Switzerland
  • Kahlert, Christian R. Infectious Diseases and Hospital Epidemiology, Children’s Hospital of Eastern Switzerland, St. Gallen, Switzerland
  • Kaufmann, Laurent Service de La Santé Publique, Canton de Neuchâtel, Neuchâtel, Switzerland
  • Kohler, Philipp Department of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
  • Mösli, Nicolai Swiss Tropical and Public Health Institute, Basel, Switzerland
  • Paris, Daniel Swiss Tropical and Public Health Institute, Basel, Switzerland
  • Probst-Hensch, Nicole Swiss Tropical and Public Health Institute, Basel, Switzerland
  • Rodondi, Nicolas Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland
  • Stringhini, Silvia Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland - Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland
  • Vermes, Thomas Swiss Tropical and Public Health Institute, Basel, Switzerland
  • Vollrath, Fabian Corona Immunitas Program Management Group, Swiss School of Public Health, Zurich, Switzerland
  • the Corona Immunitas Research Group
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    01.12.2020
Published in:
  • International Journal of Public Health. - 2020, vol. 65, no. 9, p. 1529–1548
English Objectives Seroprevalence studies to assess the spread of SARS-CoV-2 infection in the general population and subgroups are key for evaluating mitigation and vaccination policies and for understanding the spread of the disease both on the national level and for comparison with the international community. Methods Corona Immunitas is a research program of coordinated, population-based, seroprevalence studies implemented by Swiss School of Public Health (SSPH+). Over 28,340 participants, randomly selected and age-stratified, with some regional specificities will be included. Additional studies in vulnerable and highly exposed subpopulations are also planned. The studies will assess population immunological status during the pandemic. Results Phase one (first wave of pandemic) estimates from Geneva showed a steady increase in seroprevalence up to 10.8% (95% CI 8.2–13.9, n = 775) by May 9, 2020. Since June, Zurich, Lausanne, Basel City/Land, Ticino, and Fribourg recruited a total of 5973 participants for phase two thus far. Conclusions Corona Immunitas will generate reliable, comparable, and high-quality serological and epidemiological data with extensive coverage of Switzerland and of several subpopulations, informing health policies and decision making in both economic and societal sectors. ISRCTN Registry: https://www.isrctn.com/ISRCTN18181860
Faculty
Faculté des sciences et de médecine
Department
Master en médecine
Language
  • English
Classification
Medicine
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/309149
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