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Journal article

Epidemiology and diagnostics of carbapenem resistance in gram-negative bacteria

  • Nordmann, Patrice Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science and Medicine, University of Fribourg, Switzerland - Institut National de la Santé et de la Recherche Médicale European Unit, University of Fribourg, Switzerland - Swiss National Reference Center for Emerging Antibiotic Resistance, University of Fribourg, Switzerland - Institute for Microbiology, University of Lausanne and University Hospital Centre, Lausanne, Switzerland
  • Poirel, Laurent Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science and Medicine, University of Fribourg, Switzerland - Institut National de la Santé et de la Recherche Médicale European Unit, University of Fribourg, Switzerland - Swiss National Reference Center for Emerging Antibiotic Resistance, University of Fribourg, Switzerland
    13.11.2019
Published in:
  • Clinical Infectious Diseases. - 2019, vol. 69, no. Supplement_7, p. S521–S528
English Carbapenem resistance in gram-negative bacteria has caused a global epidemic that continues to grow. Although carbapenemase-producing Enterobacteriaceae have received the most attention because resistance was first reported in these pathogens in the early 1990s, there is increased awareness of the impact of carbapenem- resistant nonfermenting gram-negative bacteria, such as Acinetobacter baumannii, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia. Moreover, evaluating the problem of carbapenem resistance requires the consideration of both carbapenemase-producing bacteria as well as bacteria with other carbapenem resistance mechanisms. Advances in rapid diagnostic tests to improve the detection of carbapenem resistance and the use of large, population-based datasets to capture a greater proportion of carbapenem-resistant organisms can help us gain a better understanding of this urgent threat and enable physicians to select the most appropriate antibiotics.
Faculty
Faculté des sciences et de médecine
Department
Médecine 3ème année
Language
  • English
Classification
Biological sciences
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/308367
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