Are integrins still practicable targets for anti-cancer therapy?
- Alday-Parejo, Begoña Pathology Unit, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Switzerland
- Stupp, Roger Departments of Neurological Surgery, Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Neurology and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
- Rüegg, Curzio Pathology Unit, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Switzerland
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2019
Published in:
- Cancers. - 2019, vol. 11, no. 7, p. 978
English
Correlative clinical evidence and experimental observations indicate that integrin adhesion receptors, in particular those of the αV family, are relevant to cancer cell features, including proliferation, survival, migration, invasion, and metastasis. In addition, integrins promote events in the tumor microenvironment that are critical for tumor progression and metastasis, including tumor... Show more…
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biology
- License
- License undefined
- Identifiers
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- RERO DOC 327455
- DOI 10.3390/cancers11070978
- Persistent URL
- https://folia.unifr.ch/unifr/documents/308266