Counting calories in Drosophila diet restriction
- Min, Kyung-Jin Brown University
- Flatt, Thomas Brown University
- Kulaots, Indrek Brown University
- Tatar, Marc Brown University
-
2006
Published in:
- Experimental Gerontology. - 2006, vol. 42, no. 3, p. 247-251
English
The extension of life span by diet restriction in Drosophila has been argued to occur without limiting calories. Here we directly measure the calories assimilated by flies when maintained on full- and restricted-diets. We find that caloric intake is reduced on all diets that extend life span. Flies on low-yeast diet are long-lived and consume about half the calories of flies on high-yeast diets, regardless of the energetic content of the diet itself. Since caloric intake correlates with yeast concentration and thus with the intake of every metabolite in this dietary component, it is premature to conclude for Drosophila that calories do not explain extension of life span.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Biologie
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 324322
- DOI 10.1016/j.exger.2006.10.009
- Persistent URL
- https://folia.unifr.ch/unifr/documents/307695
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