Toolbox for in vivo imaging of host–parasite interactions at multiple scales
- Niz, Mariana De Institute of Cell Biology – Heussler Laboratory, University of Bern, Switzerland - Wellcome Centre for Molecular Parasitology, University of Glasgow, UK - Instituto de Medicina Molecular – João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
- Spadin, Florentin Institute of Applied Physics, University of Bern, Switzerland
- Marti, Matthias Wellcome Centre for Molecular Parasitology, University of Glasgow, UK
- Stein, Jens V. Theodor Kocher Institute, University of Bern, Switzerland - Department of Oncology, Microbiology and Immunology, University of Fribourg, Switzerland
- Frenz, Martin Institute of Applied Physics, University of Bern, Switzerland
- Frischknecht, Friedrich Integrative Parasitology, Centre for Infectious Diseases, Heidelberg University Medical School, Heidelberg, Germany
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01.03.2019
Published in:
- Trends in Parasitology. - 2019, vol. 35, no. 3, p. 193–212
English
Animal models have for long been pivotal for parasitology research. Over the last few years, techniques such as intravital, optoacoustic and magnetic resonance imaging, optical projection tomography, and selective plane illumination microscopy developed promising potential for gaining insights into host–pathogen interactions by allowing different visualization forms in vivo and ex vivo. Advances including increased resolution, penetration depth, and acquisition speed, together with more complex image analysis methods, facilitate tackling biological problems previously impossible to study and/or quantify. Here we discuss advances and challenges in the in vivo imaging toolbox, which hold promising potential for the field of parasitology.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 324357
- DOI 10.1016/j.pt.2019.01.002
- Persistent URL
- https://folia.unifr.ch/unifr/documents/307656
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