Magneto-responsive cell culture substrates that can be modulated in situ
- Crippa, Federica Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland
- Rothen-Rutishauser, Barbara Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland
- Petri-Fink, Alke Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland - Chemistry Department, University of Fribourg, Switzerland
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27.02.2019
Published in:
- CHIMIA International Journal for Chemistry. - 2019, vol. 73, no. 1, p. 51–54
English
Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in topography or mechanics. Herein, we describe the development of a dynamic cell culture substrate where mechanical properties are reversibly tuned in situ using magnetically- responsive superparamagnetic iron oxide nanoparticles (SPIONs).
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Chimie, AMI - Bio-Nanomatériaux
- Language
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- English
- Classification
- Chemistry
- License
- License undefined
- Identifiers
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- RERO DOC 324664
- DOI 10.2533/chimia.2019.51
- Persistent URL
- https://folia.unifr.ch/unifr/documents/307639
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