Journal article

Magneto-responsive cell culture substrates that can be modulated in situ

  • Crippa, Federica Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland
  • Rothen-Rutishauser, Barbara Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland
  • Petri-Fink, Alke Adolphe Merkle Institute, Faculty of Science and Medicine, University of Fribourg, Switzerland - Chemistry Department, University of Fribourg, Switzerland
    27.02.2019
Published in:
  • CHIMIA International Journal for Chemistry. - 2019, vol. 73, no. 1, p. 51–54
English Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in topography or mechanics. Herein, we describe the development of a dynamic cell culture substrate where mechanical properties are reversibly tuned in situ using magnetically- responsive superparamagnetic iron oxide nanoparticles (SPIONs).
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/307639
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