Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma
- Wu, Licun Division of Thoracic Surgery, University Health Network, Toronto, Canada - Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
- Blum, Walter Department of Medicine, Unit of Anatomy, University of Fribourg, Switzerland - INSERM, U1162, Paris, France
- Zhu, Chang-Qi Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
- Yun, Zhihong Division of Thoracic Surgery, University Health Network, Toronto, Canada
- Pecze, László Department of Medicine, Unit of Anatomy, University of Fribourg, Switzerland
- Kohno, Mikihiro Division of Thoracic Surgery, University Health Network, Toronto, Canada
- Chan, Mei-Lin Division of Thoracic Surgery, University Health Network, Toronto, Canada
- Zhao, Yidan Division of Thoracic Surgery, University Health Network, Toronto, Canada
- Felley-Bosco, Emanuela Laboratory of Molecular Oncology, University Hospital Zurich, Switzerland
- Schwaller, Beat Department of Medicine, Unit of Anatomy, University of Fribourg, Switzerland
- Perrot, Marc de Division of Thoracic Surgery, University Health Network, Toronto, Canada - Princess Margaret Cancer Centre, University Health Network, Toronto, Canada - Division of Thoracic Surgery, Toronto General Hospital, Canada
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27.04.2018
Published in:
- BMC Cancer. - 2018, vol. 18, p. 471
English
Cancer cell repopulation during chemotherapy or radiotherapy is a major factor limiting the efficacy of treatment. Cancer stem cells (CSC) may play critical roles during this process. We aim to demonstrate the role of mesothelioma stem cells (MSC) in treatment failure and eventually to design specific target therapies against MSC to improve the efficacy of treatment in malignant mesothelioma.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 309529
- DOI 10.1186/s12885-018-4354-1
- Persistent URL
- https://folia.unifr.ch/unifr/documents/306764
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