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Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues

  • Humberg, Tim-Henning Department of Biology, University of Fribourg, Switzerland
  • Bruegger, Pascal Department of Biology, University of Fribourg, Switzerland
  • Afonso, Bruno Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA
  • Zlatic, Marta Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA - Department of Zoology, University of Cambridge, UK
  • Truman, James W. Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA
  • Gershow, Marc Department of Physics and Center for Neural Science, New York University, USA
  • Samuel, Aravinthan Department of Physics and Center for Brain Science, Harvard University, Cambridge, MA, USA
  • Sprecher, Simon G. Department of Biology, University of Fribourg, Switzerland
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    28.03.2018
Published in:
  • Nature Communications. - 2018, vol. 9, no. 1, p. 1260
English To integrate changing environmental cues with high spatial and temporal resolution is critical for animals to orient themselves. Drosophila larvae show an effective motor program to navigate away from light sources. How the larval visual circuit processes light stimuli to control navigational decision remains unknown. The larval visual system is composed of two sensory input channels, Rhodopsin5 (Rh5) and Rhodopsin6 (Rh6) expressing photoreceptors (PRs). We here characterize how spatial and temporal information are used to control navigation. Rh6-PRs are required to perceive temporal changes of light intensity during head casts, while Rh5-PRs are required to control behaviors that allow navigation in response to spatial cues. We characterize how distinct behaviors are modulated and identify parallel acting and converging features of the visual circuit. Functional features of the larval visual circuit highlight the principle of how early in a sensory circuit distinct behaviors may be computed by partly overlapping sensory pathways.
Faculty
Faculté des sciences et de médecine
Department
Département de Biologie
Language
  • English
Classification
Biological sciences
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/306519
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