Journal article

+ 1 other files

In vitro antitubercular activity of extract and constituents from the stem bark of Disthemonanthus benthamianus

  • Evina, Jean Noel Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon
  • Ngono Bikobo, Dominique Serge Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon - Department Chemie, Universität Fribourg, Switzerland
  • Zintchem, Auguste Abouem A. Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon - Department of Chemistry, Higher Training College, University of Yaoundé I, Cameroon
  • Mbabi Nyemeck II, Norbert Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon - Faculty of Chemistry, Philipps-Universität Marburg, Germany
  • Moni Ndedi, Esther Del Florence Department of Microbiology, Faculty of Science, University of Yaoundé I, Cameroon
  • Betote Diboué, Patrick Hervé Department of Microbiology, Faculty of Science, University of Yaoundé I, Cameroon
  • Nyegue, Maximilienne Ascension Department of Microbiology, Faculty of Science, University of Yaoundé I, Cameroon
  • Atchadé, Alex de Théodore Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon
  • Pegnyemb, Dieudonné Emmanuel Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Cameroon
  • Koert, Ulrich Faculty of Chemistry, Philipps-Universität Marburg, Germany
  • Bochet, Christian G. Department Chemie, Universität Fribourg, Switzerland
Show more…
    01.11.2017
Published in:
  • Revista Brasileira de Farmacognosia. - 2017, vol. 27, no. 6, p. 739-743
English A new C-glycosylflavone, apigenin 7-methyl ether 6-C-[β-xylopyranosyl-(1→3)-β- glucopyranoside] named distemonanthoside was isolated from the stem bark of Distemonanthus benthamianus Baill., Fabaceae, along with six known compounds, sitosterol 3-O-β-d-glucopyranoside, 4-methoxygallic acid, syringic acid, quercetin, 6″- O-acetylvitexin, quercetin 3-O-β-d-glucopyranoside. The structures of those compounds and others were determined through spectral analyses. Compounds distemonanthoside, sitosterol 3-O-β-d-glucopyranoside, 4-methoxygallic acid and quercetin were tested against a clinical isolate strain of Mycobacterium tuberculosis AC 45; they exhibited good to moderate antitubercular activities with MIC values ranged from 31.25 to 125μg/ml.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Therapeutic, pharmacy, pharmacology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/306265
Other files

Statistics

Document views: 6 File downloads:
  • boc_vaa.pdf: 2
  • boc_vaa_sm.pdf: 0