Journal article

Emergence of an MDR Klebsiella pneumoniae ST231 producing OXA-232 and RmtF in Switzerland

  • Mancini, Stefano Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland
  • Poirel, Laurent Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland
  • Tritten, Marie-Lise ADMED Microbiologie, La Chaux-de-Fonds, Switzerland
  • Lienhard, Reto ADMED Microbiologie, La Chaux-de-Fonds, Switzerland
  • Bassi, Cécile Médecine Interne, Hô pital du Jura Bernois, St-Imier, Switzerland
  • Nordmann, Patrice Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland - Institute of Microbiology, University of Lausanne and UniversityHospital Center, Lausanne, Switzerland
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    2017
Published in:
  • Journal of Antimicrobial Chemotherapy. - 2017
English The increasing incidence of carbapenem-resistant Klebsiella pneumoniae is a major challenge to public health. Despite the fact that the prevalence of carbapenemases among carbapenem-resistant K. pneumoniae varies geographically, the incidence of OXA-48-like enzymes has soared in recent years and is particularly high in some European countries, such as Spain and France (74% and 78% among carbapenemase-producing K. pneumoniae, respectively).1 A significant number of OXA-48 variants have been reported in the last decade. This includes OXA-232, a carbapenemase firstly identified in France in 20112 and thereafter found in several countries.3,4 Recently, an MDR K. pneumoniae ST231 co-producing OXA-232, the ESBL CTX-M-15 and the 16S rRNA methyltransferase RmtF conferring broad- spectrum resistance to aminoglycosides has emerged as a successful epidemic...
Faculty
Faculté des sciences et de médecine
Department
Médecine 3ème année
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/306216
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