Journal article
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Biodistribution of single and aggregated gold nanoparticles exposed to the human lung epithelial tissue barrier at the air-liquid interface
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Durantie, Estelle
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Vanhecke, Dimitri
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Rodriguez-Lorenzo, Laura
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Delhaes, Flavien
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Balog, Sandor
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Septiadi, Dedy
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Bourquin, Joel
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Petri-Fink, Alke
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland - Chemistry Department, University of Fribourg, Switzerland
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Rothen-Rutishauser, Barbara
BioNanomaterials Group, Adolphe Merkle Institute, Université de Fribourg, Switzerland
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Published in:
- Particle and Fibre Toxicology. - 2017, vol. 14, p. 49
English
The lung represents the primary entry route for airborne particles into the human body. Most studies addressed possible adverse effects using single (nano)particles, but aerosolic nanoparticles (NPs) tend to aggregate and form structures of several hundreds nm in diameter, changing the physico-chemical properties and interaction with cells. Our aim was to investigate how aggregation might affect the biodistribution; cellular uptake and translocation over time of aerosolized NPs at the air-blood barrier interface using a multicellular lung system.
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Faculty
- Faculté des sciences et de médecine
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Department
- Département de Chimie
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Language
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Classification
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Biological sciences
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/306165
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