Journal article

+ 1 other files

Photochemical C–H activation: generation of indole and carbazole libraries, and first total synthesis of clausenawalline D

  • Alimi, Isak Department of Chemistry, University of Fribourg, Switzerland
  • Remy, Richard Department of Chemistry, University of Fribourg, Switzerland
  • Bochet, Christian G. Department of Chemistry, University of Fribourg, Switzerland
    16.06.2017
Published in:
  • European Journal of Organic Chemistry. - 2017, vol. 2017, no. 22, p. 3197–3210
English The photolysis of N-aryltriazoles and N-arylbenzotriazoles leads to indoles and carbazoles, respectively. Because libraries of triazoles can be accessed rapidly, for example by the copper-catalyzed [3+2] cycloaddition reaction between alkynes and azides, this reaction allows the preparation of indoles in a single operation, by the simultaneous photolysis of the precursor library. As an example of such a synthesis of carbazoles, we prepared for the first time clausenawalline D, an antimalarial alkaloid that was recently isolated.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/305979
Other files

Statistics

Document views: 9 File downloads:
  • boc_pca.pdf: 3
  • boc_pca_sm.pdf: 0