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Organization of the Drosophila larval visual circuit

  • Larderet, Ivan Department of Biology, University of Fribourg, Switzerland
  • Fritsch, Pauline Department of Biology, University of Fribourg, Switzerland
  • Gendre, Nanaë Department of Biology, University of Fribourg, Switzerland
  • Maier, G. Larisa Department of Biology, University of Fribourg, Switzerland
  • Fetter, Rick D. Howard Hughes Medical Institute at Janelia Research Campus, Ashburn, Virginia, USA
  • Schneider-Mizell, Casey Howard Hughes Medical Institute at Janelia Research Campus, Ashburn, Virginia, USA
  • Truman, James Howard Hughes Medical Institute at Janelia Research Campus, Ashburn, Virginia, USA
  • Zlatic, Marta Howard Hughes Medical Institute at Janelia Research Campus, Ashburn, Virginia, USA
  • Cardona, Albert Howard Hughes Medical Institute at Janelia Research Campus, Ashburn, Virginia, USA
  • Sprecher, Simon G. Department of Biology, University of Fribourg, Switzerland
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    05.05.2017
English Visual systems transduce, process and transmit light-dependent environmental cues. Computation of visual features depends on the types of photoreceptor neurons (PR) present, the organization of the eye and the wiring of the underlying neural circuit. Here, we describe the circuit architecture of the visual system of Drosophila larvae by mapping the synaptic wiring diagram and neurotransmitters. By contacting different targets, the two larval PR-subtypes create parallel circuits potentially underlying the computation of absolute light intensity and temporal light changes already within this first visual processing center. Locally processed visual information then signals via dedicated projection interneurons to higher brain areas including the lateral horn and mushroom body. The stratified structure of the LON suggests common organizational principles with the adult fly and vertebrate visual systems. The complete synaptic wiring diagram of the LON paves the way to understanding how circuits with reduced numerical complexity control wide ranges of behaviors.
Faculty
Faculté des sciences et de médecine
Department
Département de Biologie
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/305407
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