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Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens

  • Lattuada, Marco Adolphe Merkle Institute, University of Fribourg, Switzerland - Chemistry Department, University of Fribourg, Switzerrland
  • Ren, Q. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
  • Zuber, F. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
  • Galli, M. Dipartimento di Chimica, Università degli Studi di Milano, Italy
  • Bohmer, N. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
  • Matter, M. T. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
  • Wichser, A. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
  • Bertazzo, S. Department of Medical Physics and Biomedical Engineering, University College London, UK
  • Pier, G. B. Brigham and Women's Hospital, Boston, USA
  • Herrmann, Inge K. Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland
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    09.11.2016
Published in:
  • Journal of Materials Chemistry B. - 2016, vol. 4, no. 44, p. 7080–7086
English We report on theoretical and experimental considerations on bacteria capturing and enrichment via magnetic separation enabling integrated diagnosis and treatment of blood stream infections. We show optimization of carrier-pathogen interactions based on a mathematical model followed by an experimental proof-of-concept study along with investigations on the process safety.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/305353
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