Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients
- Coetzee, Jennifer Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
- Corcoran, Craig Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
- Prentice, Elizabeth Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
- Moodley, Mischka Ampath National Laboratory Services, Cape Town, South Africa
- Mendelson, Marc Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
- Poirel, Laurent Unit of Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
- Nordmann, Patrice Unit of Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
- Brink, Adrian John Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
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19.04.2016
Published in:
- South African Medical Journal. - 2016, vol. 106, no. 5, p. 449–450
English
The polymyxin antibiotic colistin is an antibiotic of last resort for the treatment of extensively drug-resistant Gram-negative bacteria, including carbapenemase- producing Enterobacteriaceae. The State of the World’s Antibiotics report in 2015 highlighted South Africa (SA)’s increasing incidence of these ‘superbugs’ (3.2% of Klebsiella pneumoniae reported from SA were carbapenemase producers), and in doing so, underscored SA’s increasing reliance on colistin as a last line of defence. Colistin resistance effectively renders such increasingly common infections untreatable.
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 259489
- DOI 10.7196/SAMJ.2016.v106i5.10710
- Persistent URL
- https://folia.unifr.ch/unifr/documents/304996
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