Journal article

Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients

  • Coetzee, Jennifer Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
  • Corcoran, Craig Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
  • Prentice, Elizabeth Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
  • Moodley, Mischka Ampath National Laboratory Services, Cape Town, South Africa
  • Mendelson, Marc Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
  • Poirel, Laurent Unit of Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
  • Nordmann, Patrice Unit of Molecular Microbiology, Department of Medicine, University of Fribourg, Switzerland
  • Brink, Adrian John Departments of Clinical Microbiology and Molecular Sciences, Ampath Reference Laboratory, Centurion, Pretoria, South Africa
Show more…
    19.04.2016
Published in:
  • South African Medical Journal. - 2016, vol. 106, no. 5, p. 449–450
English The polymyxin antibiotic colistin is an antibiotic of last resort for the treatment of extensively drug-resistant Gram-negative bacteria, including carbapenemase- producing Enterobacteriaceae. The State of the World’s Antibiotics report in 2015 highlighted South Africa (SA)’s increasing incidence of these ‘superbugs’ (3.2% of Klebsiella pneumoniae reported from SA were carbapenemase producers), and in doing so, underscored SA’s increasing reliance on colistin as a last line of defence. Colistin resistance effectively renders such increasingly common infections untreatable.
Faculty
Faculté des sciences et de médecine
Department
Médecine 3ème année
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/304996
Statistics

Document views: 4 File downloads:
  • nor_epm.pdf: 1