Emergence of Escherichia coli producing OXA-48 β-lactamase in the community in Switzerland
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Zurfluh, Katrin
Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Switzerland
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Nüesch-Inderbinen, Magdalena T
Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Switzerland
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Poirel, Laurent
Medical and Molecular Microbiology Unit , Dept of Medicine, University of Fribourg, Fribourg, Switzerland
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Nordmann, Patrice
Medical and Molecular Microbiology Unit , Dept of Medicine, University of Fribourg, Fribourg, Switzerland
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Hächler, Herbert
Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Switzerland
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Stephan, Roger
Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Switzerland
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Published in:
- Antimicrobial Resistance and Infection Control. - 2016, vol. 4, p. 9
English
The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in the community in Switzerland.Findings: One thousand and eighty-six stool samples of healthy humans (staff members of a food-processing company which were screened for the occurrence of salmonellae) were collected in September 2014. After an initial enrichment-step, carbapenemase-producing Enterobacteriaceae were isolated from the carbapenem-containing selective medium SUPERCARBA II. Grown colonies from 11 samples were screened by PCR for the presence of bla KPC, bla NDM, bla OXA-48 and bla VIM. A single OXA-48-producing Escherichia coli was detected. Phylogenetic grouping and multi-locus sequence typing (MLST) revealed that this strain belonged to D:ST38, a type which had been previously reported in the UK, France, Lebanon and Egypt.Conclusions: The results of this study show that OXA-48-producing Enterobacteriaceae have started to spread into the community in Switzerland, and a continuous monitoring is necessary to better understand their dissemination in the human population as well as in animals and the environment.
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Faculty
- Faculté des sciences et de médecine
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Department
- Médecine 3ème année
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Language
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Classification
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Biological sciences
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/304992
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