Journal article

Synthesis of new polyether ether ketone derivatives with silver binding site and coordination compounds of their monomers with different silver salts

  • Girard, Jérôme Department of Chemistry, University of Fribourg, Switzerland
  • Joset, Nathalie Department of Chemistry, University of Fribourg, Switzerland
  • Crochet, Aurélien Fribourg Center for Nanomaterials, FriMat, Department of Physics, University of Fribourg, Switzerland
  • Tan, Milène Department of Chemistry, University of Fribourg, Switzerland
  • Holzheu, Anja Department of Chemistry, University of Fribourg, Switzerland
  • Brunetto, Priscilla S. Department of Chemistry, University of Fribourg, Switzerland
  • Fromm, Katharina M. Department of Chemistry, University of Fribourg, Switzerland
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    30.05.2016
Published in:
  • Polymers. - 2016, vol. 8, no. 6, p. 208
English Polyether ether ketone (PEEK) is a well-known polymer used for implants and devices, especially spinal ones. To overcome the biomaterial related infection risks, 4-4′- difluorobenzophenone, the famous PEEK monomer, was modified in order to introduce binding sites for silver ions, which are well known for their antimicrobial activity. The complexation of these new monomers with different silver salts was studied. Crystal structures of different intermediates were obtained with a linear coordination between two pyridine groups and the silver ions in all cases. The mechanical and thermal properties of different new polymers were characterized. The synthesized PEEKN5 polymers showed similar properties than the PEEK ones whereas the PEEKN7 polymers showed similar thermal properties but the mechanical properties are not as good as the ones of PEEK. To improve these properties, these polymers were complexed with silver nitrate in order to “cross-link” with silver ions. The presence of ionic silver in the polymer was then confirmed by thermogravimetric analysis (TGA) and X-ray powder diffraction (XRPD). Finally, a silver-based antimicrobial compound was successfully coated on the surface of PEEKN5.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/304965
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