Supramolecular agent–simulant correlations for the luminescence based detection of V-series chemical warfare agents with trivalent lanthanide complexes
- Dennison, Genevieve H. Land Division, Defence Science and Technology Group, Fishermans Bend Melbourne , Australia - Flinders Centre for Nanoscale Science and Technology, School of Chemical and Physical Sciences, Flinders University Adelaide, Australia
- Bochet, Christian G. Department of Chemistry, University of Fribourg, Switzerland
- Curty, Christophe Organic Chemistry Branch, Federal Office of Civil Protection (FOCP), Spiez, Switzerland
- Ducry, Julien Department of Chemistry, University of Fribourg, Switzerland - Organic Chemistry Branch, Federal Office of Civil Protection (FOCP), Spiez, Switzerland
- Nielsen, David J. Land Division, Defence Science and Technology Group, Fishermans Bend Melbourne , Australia
- Sambrook, Mark R. CBR Division, Defence Science and Technology Laboratory, Porton Down, United Kingdom
- Zaugg, Andreas Organic Chemistry Branch, Federal Office of Civil Protection (FOCP), Spiez, Switzerland
- Johnston, Martin R. Flinders Centre for Nanoscale Science and Technology, School of Chemical and Physical Sciences, Flinders University Adelaide, Australia
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01.03.2016
Published in:
- European Journal of Inorganic Chemistry. - 2016, vol. 2016, no. 9, p. 1348-1358
English
Solution spectroscopic investigations into the interactions of eight potential bidentate V-series organophosphorus chemical warfare agent (OP CWA) simulants with [Eu(phen)₂(NO₃)₃]·2H₂O demonstrated that the chemical and structural composition of the secondary binding site within the simulant was of paramount importance. Only simulants containing both phosphoryl/phosphonyl and amine moieties generated analogous spectroscopic behaviours to V-series OP CWAs seen in previous studies. The results demonstrated that the bidentate chelation mechanism was driven by the phosphoryl/phosphonyl moieties and that the presence of the amine moieties induced a significant secondary dynamic luminescence quenching mechanism. The binding modes of the simulants VO and TEEP to trivalent lanthanides (Eu and La) were further investigated using ¹H and ³¹P NMR spectroscopic titrations and kinetic IR experiments. VO, with both the phosphonyl and amine binding sites was found to be the most appropriate simulant for V-series OP CWAs in supramolecular studies with trivalent lanthanide ions and we recommend VO for use in supramolecular studies of this type.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Chimie
- Language
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- English
- Classification
- Chemistry
- License
- License undefined
- Identifiers
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- RERO DOC 258811
- DOI 10.1002/ejic.201600105
- Persistent URL
- https://folia.unifr.ch/unifr/documents/304911
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