About the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing Escherichia coli

Zahar, Jean-Ralph; Poirel, Laurent; Dupont, Claire; Fortineau, Nicolas; Nassif, Xavier; Nordmann, Patrice

doi:10.1186/s12879-015-1244-x

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Journal article

About the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing Escherichia coli

Zahar, Jean-Ralph Infection Control Unit, CHU Angers, Angers, France. - Service de Microbiologie-Hygiène, Hôpital Necker-Enfants-Malades, Paris, France.
Poirel, Laurent Service de Bactériologie - Hygiène, Hôpital de Bicêtre, K.-Bicêtre, France. - Department of Medicine, Medical and Molecular Microbiology « Emerging Antibiotic Resistance » Unit, University of Fribourg, Switzerland
Dupont, Claire Service de Bactériologie - Hygiène, Hôpital de Bicêtre, K.-Bicêtre, France.
Fortineau, Nicolas Service de Bactériologie - Hygiène, Hôpital de Bicêtre, K.-Bicêtre, France.
Nassif, Xavier Service de Microbiologie-Hygiène, Hôpital Necker-Enfants-Malades, Paris, France.
Nordmann, Patrice Service de Bactériologie - Hygiène, Hôpital de Bicêtre, K.-Bicêtre, France. - Department of Medicine, Medical and Molecular Microbiology « Emerging Antibiotic Resistance » Unit, University of Fribourg, Switzerland

2015

Published in:

BMC Infectious Diseases. - 2015, vol. 15, p. 512

English Extended-spectrum β-lactamases producing Escherichia coli (ESBL-E) are increasingly identified in health care facilities. As previously done for the control of methicillin-resistant Staphylococcus aureus, many hospitals have established screening strategies for early identification of patients being carriers of ESBL producers in general and ESBL-E in particular, and have implemented contact precautions (CP) for infected and colonized patients.Methods: The incidence of ESBL-E has been compared retrospectively between two French university hospitals (A and B) with different infection control policies over a 5-year long period of time (2006–2010).Results: While hospital A only implemented standard precautions after identification of patients colonized with ESBL-E, hospital B recommended additional CP. During the period of the study, the ESBL-E incidence rate significantly increased in both hospitals, but no significant difference was observed between the two hospitals.Conclusions: This observational study did not reveal that additional CP measures had a greater impact on the incidence of ESBL-E in hospital settings.

Faculty

Faculté des sciences et de médecine

Department

Médecine 3ème année

Language