Laser Speckle Imaging of Cerebral Blood Flow
- Zakharov, Pavel Physics Institute, University of Fribourg, Switzerland
- Scheffold, Frank Department of Physics and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
- Weber, Bruno Institute of Pharmacology and Toxicology, University of Zurich, Switzerland
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01.01.2014
Published in:
- Optical Imaging of Neocortical Dynamics. - 2014, vol. 85, p. 255–271
English
Optical imaging of cerebral hemodynamics has been used extensively to investigate the complex interplay between neurons and the blood-borne supply of oxygen and energy substrates. Among several techniques, the so-called laser speckle imaging (LSI) has found widespread applications for studying (patho-)physiological aspects of neurovascular coupling. LSI is a rather simple and cost-effective method to acquire two-dimensional maps of cerebral blood flow from the cortex of experimental animals. In this chapter, we introduce the physical underpinnings as well as the most important technical and practical aspects of its implementation.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Physique
- Language
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- English
- Classification
- Physics
- License
- License undefined
- Identifiers
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- RERO DOC 231809
- DOI 10.1007/978-1-62703-785-3_15
- Persistent URL
- https://folia.unifr.ch/unifr/documents/303860
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