Journal article

Coaxiality of Foxb1- and parvalbumin-expressing neurons in the lateral hypothalamic PV1-nucleus

  • Bilella, Alessandro Anatomy Unit, Department of Medicine and Program in Neuroscience, University of Fribourg, Switzerland
  • Alvarez-Bolado, Gonzalo Institute of Anatomy and Cell Biology, University of Heidelberg, Germany
  • Celio, Marco R. Anatomy Unit, Department of Medicine and Program in Neuroscience, University of Fribourg, Switzerland
    30.04.2014
Published in:
  • Neuroscience Letters. - 2014, vol. 566, p. 111–114
English In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region that is occupied by the PV1-nucleus. They formed a cloud around the axial cord of the parvalbumin-immunopositive cells, which they greatly outnumber (3:1). Only a small proportion of the neurons in the PV1-nucleus co-expressed both parvalbumin and Foxb1. In the light of these findings, a redesignation of this lateral hypothalamic structure as the PV1-Foxb1 nucleus would more accurately reflect its specific biochemical properties.
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/303840
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