Coaxiality of Foxb1- and parvalbumin-expressing neurons in the lateral hypothalamic PV1-nucleus
- Bilella, Alessandro Anatomy Unit, Department of Medicine and Program in Neuroscience, University of Fribourg, Switzerland
- Alvarez-Bolado, Gonzalo Institute of Anatomy and Cell Biology, University of Heidelberg, Germany
- Celio, Marco R. Anatomy Unit, Department of Medicine and Program in Neuroscience, University of Fribourg, Switzerland
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30.04.2014
Published in:
- Neuroscience Letters. - 2014, vol. 566, p. 111–114
Medial forebrain bundle
hypothalamic development
immunohistochemistry
stereology
periaqueductal grey
English
In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region that is occupied by the PV1-nucleus. They formed a cloud around the axial cord of the parvalbumin-immunopositive cells, which they greatly outnumber (3:1). Only a small proportion of the neurons in the PV1-nucleus co-expressed both parvalbumin and Foxb1. In the light of these findings, a redesignation of this lateral hypothalamic structure as the PV1-Foxb1 nucleus would more accurately reflect its specific biochemical properties.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 211456
- DOI 10.1016/j.neulet.2014.02.028
- Persistent URL
- https://folia.unifr.ch/unifr/documents/303840
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