OXA-253, a variant of the carbapenem-hydrolyzing class D β-Lactamase OXA-143 in Acinetobacter baumannii

Girlich, Delphine; Damaceno, Quésia S.; Oliveira, Adriana Cristina; Nordmann, Patrice

doi:10.1128/AAC.02640-13

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Journal article

OXA-253, a variant of the carbapenem-hydrolyzing class D β-Lactamase OXA-143 in Acinetobacter baumannii

Girlich, Delphine INSERM U914 Emerging Resistance to Antibiotics, Kremlin-Bicêtre, France
Damaceno, Quésia S. Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Oliveira, Adriana Cristina Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Nordmann, Patrice INSERM U914 Emerging Resistance to Antibiotics, Kremlin-Bicêtre, France - Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland

05.01.2014

Published in:

Antimicrobial Agents and Chemotherapy. - 2014, vol. 58, no. 5, p. 2976–2978

English The carbapenem-hydrolyzing class D β-lactamase OXA-253 was identified in an Acinetobacter baumannii clinical isolate belonging to sequence type 113 (ST113) in Brazil. OXA-253 shares 93.8% amino acid identity with OXA-143. The bla_OXA-253 gene is located on a ca. 20-kb plasmid. The genetic environment of the bla_OXA-253 gene shares the highest identity with ubiquitous GR2 group plasmids usually carrying bla_OXA-24/-40 genes.

Faculty

Faculté des sciences et de médecine

Department

Médecine 3ème année

Language