Journal article

Outbreak caused by NDM-1- and RmtB-producing Escherichia coli in Bulgaria

  • Poirel, Laurent Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, K.-Bicêtre, France
  • Savov, Encho Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
  • Nazli, Arzu Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland
  • Trifonova, Angelina Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
  • Todorova, Iva Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
  • Gergova, Ivanka Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
  • Nordmann, Patrice Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, K.-Bicêtre, France
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    04.01.2014
Published in:
  • Antimicrobial Agents and Chemotherapy. - 2014, vol. 58, no. 4, p. 2472–2474
English Twelve consecutive carbapenem-resistant Escherichia coli isolates were recovered from patients (infection or colonization) hospitalized between March and September 2012 in different units at a hospital in Bulgaria. They all produced the carbapenemase NDM-1 and the extended-spectrum-β-lactamase CTX-M-15, together with the 16S rRNA methylase RmtB, conferring high-level resistance to all aminoglycosides. All those isolates were clonally related and belonged to the same sequence type, ST101. In addition to being the first to identify NDM-producing isolates in Bulgaria, this is the very first study reporting an outbreak of NDM-1-producing E. coli in the world.
Faculty
Faculté des sciences et de médecine
Department
Médecine 3ème année
Language
  • English
Classification
Pathology, clinical medicine
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/303591
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