Outbreak caused by NDM-1- and RmtB-producing Escherichia coli in Bulgaria
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Poirel, Laurent
Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, K.-Bicêtre, France
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Savov, Encho
Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
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Nazli, Arzu
Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland
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Trifonova, Angelina
Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
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Todorova, Iva
Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
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Gergova, Ivanka
Laboratory of Microbiology, Military Medical Academy, Sofia, Bulgaria
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Nordmann, Patrice
Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Switzerland - INSERM U914, South-Paris Medical School, K.-Bicêtre, France
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Published in:
- Antimicrobial Agents and Chemotherapy. - 2014, vol. 58, no. 4, p. 2472–2474
English
Twelve consecutive carbapenem-resistant Escherichia coli isolates were recovered from patients (infection or colonization) hospitalized between March and September 2012 in different units at a hospital in Bulgaria. They all produced the carbapenemase NDM-1 and the extended-spectrum-β-lactamase CTX-M-15, together with the 16S rRNA methylase RmtB, conferring high-level resistance to all aminoglycosides. All those isolates were clonally related and belonged to the same sequence type, ST101. In addition to being the first to identify NDM-producing isolates in Bulgaria, this is the very first study reporting an outbreak of NDM-1-producing E. coli in the world.
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Faculty
- Faculté des sciences et de médecine
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Department
- Médecine 3ème année
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Language
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Classification
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Pathology, clinical medicine
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/303591
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