Expression of the calcium binding proteins Necab-1,-2 and -3 in the adult mouse hippocampus and dentate gyrus
- Zimmermann, B. Division of Anatomy and Program in Neuroscience, University of Fribourg, Switzerland
- Girard, Franck Division of Anatomy and Program in Neuroscience, University of Fribourg, Switzerland
- Mészàr, Zoltán Division of Anatomy and Program in Neuroscience, University of Fribourg, Switzerland
- Celio, Marco R. Division of Anatomy and Program in Neuroscience, University of Fribourg, Switzerland
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28.08.2013
Published in:
- Brain Research. - 2013, vol. 1528, p. 1–7
English
The family of EF-hand calcium binding proteins is composed of more than 250 members. In search for other neuronal markers, we studied the expression pattern of Necab-1, -2 and -3 in the Ammons horn of adult mice at the gene- and protein levels using in-situ hybridization and immunohistochemistry. The genes for the three Necab's were expressed in specific, non-overlapping areas of the hippocampus. A minority of the Necab-positive interneurons were GABA-ergic, and they virtually never coexpressed one of the classical calcium binding proteins (calretinin, calbindin D-28k and parvalbumin). Necab's are promising new neuronal markers in the brain.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Médecine
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 205540
- DOI 10.1016/j.brainres.2013.06.004
- Persistent URL
- https://folia.unifr.ch/unifr/documents/303229
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