Journal article

Rapid high resolution imaging of diffusive properties in turbid media

  • Scheffold, Frank Department of Physics and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
  • Block, Ian D. Department of Physics and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland - LS Instruments AG, Fribourg, Switzerland
    20.12.2011
Published in:
  • Optics Express. - 2012, vol. 20, no. 1, p. 192-200
English We propose a laser speckle based scheme that allows the analysis of local scattering properties of light diffusely reflected from turbid media. This turbid medium can be a soft material such as a colloidal or polymeric material but can also be biological tissue. The method provides a 2D map of the scattering properties of a complex, multiple scattering medium by recording a single image. We demonstrate that the measured speckle contrast can be directly related to the local transport mean free path l* or the reduced scattering coefficient μt = 1/l* of the medium. In comparison to some other approaches, the method does not require scanning (of a laser beam, detector or the sample itself) in order to generate a spatial map. It can conveniently be applied in a reflection geometry and provides a single characteristic value at any given position with an intrinsic resolution typically on the order of 5–50 μm. The actual resolution is however limited by the transport mean free path itself and can thus range from microns to millimeters
Faculty
Faculté des sciences et de médecine
Department
Département de Physique
Language
  • English
Classification
Physics
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/302585
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