Circadian rhythms and sleep—the metabolic connection
- Albrecht, Urs Biochemistry unit, Biology department, University of Fribourg, Switzerland
-
28.06.2011
Published in:
- Pflügers Archiv European Journal of Physiology. - 2011, vol. 463, no. 1, p. 23-30
Nuclear receptors
Neurotransmitters
Protein kinases
Metabolism
AMPK
Cell death
Apoptosis
Adenosine
ATP release
Catecholamines
cGMP
Circadian rhythm
Gene expression
Liver
Neuroendocrinology
Protein kinase
Sleep apnea
English
The circadian system coordinates mammalian physiology and behavior with the environmental light–dark cycle. It allocates sleep to the inactivity phase using various mechanisms involving neurotransmitters, nuclear receptors, and protein kinases. These pathways are related to metabolism, indicating that the circadian system and sleep are connected via metabolic parameters. This suggests that organs other than the brain may “sleep.” A hypothetic view on this aspect is presented providing a different perspective on sleep regulation.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Biologie
- Language
-
- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 27110
- DOI 10.1007/s00424-011-0986-6
- Persistent URL
- https://folia.unifr.ch/unifr/documents/302010
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