The daily rhythm of mice
- Ripperger, Jürgen A. Department of Medicine/Unit of Biochemistry, University of Fribourg, Switzerland
- Jud, Corinne Adolphe Merkle Institute, University of Fribourg, Switzerland - Department of Medicine/Unit of Biochemistry, University of Fribourg, Switzerland
- Albrecht, Urs Department of Medicine/Unit of Biochemistry, University of Fribourg, Switzerland
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21.02.2011
Published in:
- FEBS Letters. - 2011, vol. 585, no. 10, p. 1384-1392
English
The house mouse Mus musculus represents a valuable tool for the analysis and the understanding of the mammalian circadian oscillator. Forward and reverse genetics allowed the identification of clock components and the verification of their function within the circadian clockwork. In many cases unforeseen links were discovered between a particular circadian regulatory protein and various diseases or syndromes. Thus, this model system is not only perfectly suited to pinpoint the components of the mammalian circadian clock, but also to unravel metabolic, physiological, and pathological processes linked to the circadian timing system.
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Biologie
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 22249
- DOI 10.1016/j.febslet.2011.02.027
- Persistent URL
- https://folia.unifr.ch/unifr/documents/301917
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