Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats
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Boyer, Frederic
Institute of Biochemistry, University of Fribourg, Switzerland
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Dreyer, Jean-Luc
Institute of Biochemistry, University of Fribourg, Switzerland
Published in:
- European Journal of Neuroscience. - 2007, vol. 26, no. 10, p. 2764-2776
English
The mesolimbic dopaminergic system is widely recognized to be critical to the neurobiology of cocaine reward and addiction. The neuronal protein, α-synuclein, is an important regulator in dopaminergic transmission. It interacts with the dopamine transporter, and regulates dopaminergic content, neurotransmission and synaptic strength of dopaminergic neurons. Alpha-synuclein levels are elevated... Show more…
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Faculty
- Faculté des sciences
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Department
- Médecine
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Language
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Classification
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Biology
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License
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License undefined
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Identifiers
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Persistent URL
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https://folia.unifr.ch/unifr/documents/300711