Renal expression of parvalbumin is critical for NaCl handling and response to diuretics
-
Belge, Hendrica
Departments of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
-
Gailly, Philippe
Departments of Physiology, Université Catholique de Louvain Medical School, Brussels, Belgium
-
Schwaller, Beat
Unit of Anatomy, University of Fribourg, Switzerland
-
Loffing, Johannes
Unit of Anatomy, University of Fribourg, Switzerland
-
Debaix, Huguette
Departments of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
-
Riveira-Munoz, Eva
Departments of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
-
Beauwens, Renaud
Laboratory of Cell and Molecular Physiology, Université Libre de Bruxelles Medical School, Brussels, Belgium
-
Devogelaer, Jean-Pierre
Departments of Rheumatology, Université Catholique de Louvain Medical School, Brussels, Belgium
-
Hoenderop, Joost G.
Department of Physiology, Radboud University Nijmegen, The Netherlands
-
Bindels, René J.
Department of Physiology, Radboud University Nijmegen, The Netherlands
-
Devuyst, Olivier
Departments of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
Show more…
Published in:
- Proceedings of the National Academy of Sciences of the United States of America. - 2007, vol. 104, no. 37, p. 14849-14854
English
The distal convoluted tubule (DCT) plays an essential role in the reabsorption of NaCl by the kidney, a process that can be inhibited by thiazide diuretics. Parvalbumin (PV), a Ca²⁺-binding protein that plays a role in muscle fibers and neurons, is selectively expressed in the DCT, where its role remains unknown. We therefore investigated the renal phenotype of PV knockout mice... Show more…
-
Faculty
- Faculté des sciences et de médecine
-
Department
- Département de Médecine
-
Language
-
-
Classification
-
Biology
-
License
-
License undefined
-
Identifiers
-
-
Persistent URL
-
https://folia.unifr.ch/unifr/documents/300617