Journal article

β-Adrenergic control of stearoyl-CoA desaturase 1 repression in relation to sympathoadrenal regulation of thermogenesis

  • Mainieri, Davide Department of Medicine/Physiology, University of Fribourg, Switzerland
  • Montani, Jean-Pierre Department of Medicine/Physiology, University of Fribourg, Switzerland
  • Seydoux, Josiane Department of Neuroscience, Centre Médical Universitaire, Geneva, Switzerland
  • Giacobino, J. P. Department of Medical Biochemistry, Centre Médical Universitaire, Geneva, Switzerland
  • Boss, O. Sirtris Pharmaceuticals Inc., Cambridge, USA
  • Dulloo, Abdul G. Department of Medicine/Physiology, University of Fribourg, Switzerland
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    27.06.2006
Published in:
  • International Journal of Obesity. - 2007, vol. 31, no. 2, p. 378–381
English Mice lacking <i>β</i>-adrenoceptors, which mediate the thermogenic effects of norepinephrine and epinephrine, show diminished thermogenesis and high susceptibility to obesity, whereas mice lacking stearoyl-CoA desaturase 1 (SCD1), which catalyzes the synthesis of monounsaturated fatty acids, show enhanced thermogenesis and high resistance to obesity. In testing whether <i>β</i>-adrenergic... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300556