Journal article

Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells

  • Zhu, Shengsi Vascular Biology, Department of Medicine, Division of Physiology, University of Fribourg, Switzerland - Cardiovascular Department, 1st Affiliated Hospital of Dalian Medical University, Dalian, China
  • Viswambharan, Hema Vascular Biology, Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Gajanayake, Thusitha Vascular Biology, Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Ming, Xiu-Fen Vascular Biology, Department of Medicine, Division of Physiology, University of Fribourg, Switzerland -
  • Yang, Zhihong Vascular Biology, Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
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    17.07.2005
Published in:
  • BMC Cardiovascular Disorders. - 2007, vol. 5, p. 22
English Background Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis. Tissue factor (TF) is critical in thrombosis. This study investigated the effect of sirolimus on TF expression and activity in cultured human vascular smooth muscle cells... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300371