Journal article

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Mutation of the circadian clock gene Per2 alters vascular endothelial function

  • Viswambharan, Hema Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Carvas, João Miguel Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Antic, Vladan Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Marecic, Ana Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Jud, Corinne Department of Medicine, Division of Biochemistry, University of Fribourg, Switzerland
  • Zaugg, Christian E. Department of Research, University Hospital Basel, Switzerland
  • Ming, Xiu-Fen Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Montani, Jean-Pierre Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
  • Albrecht, Urs Department of Medicine, Division of Biochemistry, University of Fribourg, Switzerland
  • Yang, Zhihong Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
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    02.04.2007
Published in:
  • Circulation. - 2007, vol. 115, p. 2188-2195
English <i>Background—</i> The circadian clock regulates biological processes including cardiovascular function and metabolism. In the present study, we investigated the role of the circadian clock gene <i>Period2</i> (<i>Per2</i>) in endothelial function in a mouse model. <b><i>Methods and Results—</i></b> Compared with the wild-type littermates, mice with <i>Per2</i> mutation exhibited impaired... Show more…
Faculty
Faculté des sciences et de médecine
Department
Département de Biologie, Département de Médecine
Language
  • English
Classification
Biology
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/300364
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